WP really isn't al that difficult to set up -- my PHP skills are very limited and I was able to install it on my own with minimal fuss. I think the hardest thing was setting up the MySQL database; fortunately, my web host (Dreamhost) has a reasonably easy interface for it.

Some hosts will even auto-install WP for you. (Mine does, but that feature came after I already installed it myself.) Check out wordpress.org/hosting for recommended hosts.

My one complaint about WP is that it doesn't support multiple blogs on one installation out of the box. There are plug-ins available for that, but I think they're more complicated than they're worth.